Web Link Hits      NONMEM Project Group The NONMEM Project at the University of California, San Francisco, which produced the UCSF NONMEM software, is concerned with the development of data analysis techniques and exportable software for fitting nonlinear mixed effects (statistical regress 61      truPK The value of in silico ADME predictions, if reasonably reliable, is very clear. There have been several attempts to build informatics-based models to predict pharmacokinetic properties of drug candidates. Few have been able to claim reliability of p 79      Simcyp Ltd Simcyp® builds virtual populations incorporating extensive demographic, physiological, pathological, genetic and ethnic variability; this is used to simulate and predict the population variability of whole body kinetics and drug-drug interactions. PB 60      PKQuest A free 'one stop' pharmacokinetic program that runs on top of Maple and features detailed graphical output. 64      PK-Sim PK-Sim (R) is an integrated whole body PBPK-software offered by Bayer Technology Services GmbH. It is based on a universal PBPK-model and has a very convenient user interface for parameter setting, evaluation of results and project management. PK-Sim 80      Physiological Parameters for PBPK Modeling Version 1.01 Physiological Parameters for PBPK Modeling Version 1.01 (P³M) provides a unique source of data for human physiological parameters where 1) the parameter values for an individual are correlated with one another, and 2) values of parameters vary accord 106      Pharmacokinetic Software for Research and Education PK Solutions provides fast, easy, and comprehensive analysis of pharmacokinetic plasma level data. The program is Excel-based with virtually no learning curve. Some 75 PK parameters are computed and graphed, including extrapolation of single does res 111      Micromath Research MicroMath Research offers a complete line of scientific software including MicroMath Scientist, PKAnalyst and Chemist. We look forward to working with our valued customers to improve and enhance the entire MicroMath product line. Please check this si 46      MCSim MCSim is a simulation package which allows you to: Design your own statistical or simulation models (eventually dynamic,via ODEs), Perform Monte Carlo stochastic simulations, Make Bayesian inference through Markov Chain Monte Carlo simulations 66      Kinetica Kinetica™ is a powerful, industry-standard pharmacokinetic-pharmacodynamic (PK/PD) application for non-compartmental, fitting, simulation, population PK/PD and reporting. With an intuitive point-and-click graphical interface, Kinetica™ facilitates da 67      Design tools for the life sciences Teranode Corporation is a startup software company focused on delivering industrial-strength design tools for the life sciences. After several years of development and extensive piloting in organizations such as Pfizer, AstraZeneca and the Fred Hutch 65      Boomer Non-Linear Regression Program MULTIFORTE started as a direct FORTRAN 77 translation of the MULTI program written in BASIC by K. Yamaoka et.al [Yamaoka, 1981]. MULTI was written for a microcomputer in BASIC and allowed for the nonlinear least squares analysis of integrated equ 43      Berkeley Madonna Developed on the Berkeley campus under the sponsorship of NSF and NIH, it is currently used by academic and commercial institutions for constructing mathematical models for research and teaching. 66      acslXtreme acslXtreme is the sophisticated, next-generation tool for modeling continuous dynamic systems and processes. Simple to learn and easy to use, acslXtreme is a refreshingly modern application built on top of the latest technologies including .NET and X 59

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