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Latest PBPK papers
Theme update
Written by Martin Spendiff   
Friday, 09 May 2008
We've had a bit of a spring clean and the site should be a little easier to navigate now. If you come across any problems with the new format please let us know. There seem to be a few issues with the login process. If you are having problems please click on Contact Us and we'll reset your details.
Last Updated ( Monday, 12 May 2008 )
 
Drug Metabolism and Pharmacokinetics - closing date Friday 30th May 2008
Written by Martin Spendiff   
Wednesday, 30 April 2008
Image From Simcyp:

We have a number of immediate openings for scientists with drug metabolism and pharmacokinetics background. The candidates should have hands-on experience in using any of the in vitro systems used for assessing the oral absorption, distribution, metabolism and excretion (ADME) of drugs. Knowledge of pharmacological effects, human physiology and biology, and in particular modelling and data analysis is advantageous.

The successful applicant will join an internationally recognised, multidisciplinary team in which s/he will be expected to take part in building information around in vitro in vivo extrapolation of ADME properties and indicating its applications.

Last Updated ( Friday, 09 May 2008 )
Read more...
 
Old forum content transferred
Written by Martin Spendiff   
Wednesday, 13 February 2008
Some of the discussion from the old-style forum has now been moved across to the new forum. Owners of posts have not been preserved thanks to incompatibilities in the members lists. If you spot one of your posts and want to reclaim it just mail one of the site admins. So, if you have any discussion topics/ problems that may benefit from the attention of your fellow members, go to the forum section and add some content.
Last Updated ( Wednesday, 13 February 2008 )
 
AEgis announces substantial price reductions for acslX tools
Written by Conrad Housand   
Wednesday, 16 January 2008
ImageAEgis recently announced substantial price reductions for the acslX family of tools for modeling and simulation, which are widely used for PBPK and PK/PD modeling. The full version, which includes textual and graphical languages for specifying complex kinetics/dynamics models, and a Matlab-like scripting language for specification of parameter estimation, sensitivity analysis, Monte-Carlo, or Markov-Chain Monte Carlo analyses, is now priced starting at $500 US. The price reduction is intended to make acslX accessible to a wider community of modelers seeking an affordable high-end commercial simulation tool, and to increase the audience of potential end-users of models developed by current acslX customers. The latest version of acslX includes support for cluster/grid computing, and provides data integration capabilities with Microsoft Excel and Access. A PBPK/PK/PD toolkit is also available, and a Bayesian population modeling capability based on MCMC analysis is planned for early this year. Contact This e-mail address is being protected from spam bots, you need JavaScript enabled to view it for more information, or visit www.acslx.com.
Last Updated ( Wednesday, 23 January 2008 )
 
MEGen section added to forum
Written by Martin Spendiff   
Wednesday, 08 August 2007
An area dedicated to the discussion of HSL's recently-released PBPK model generator, MEGen, has been added to the forum section. Since MEGen is pre-alpha open-source software, intended to be a freely-available community resource. The primary purpose of the forum is for users and developers to submit code, discuss bugs, highlight issues and supply feature requests.

WARNING: MEGen is optimised for firefox, so use that if you can. Failing that, please upgrade your copy of Internet Explorer to IE7.

Last Updated ( Friday, 09 May 2008 )
 
Hands-on Workshop on Modelling and Simulation in Drug Development: Sheffield, UK.
Written by Martin Spendiff   
Thursday, 02 August 2007
BioSim EU Network of Excellence biosim-network.net together with 3 of its member organisations Simcyp Limited simcyp.com, CBG-MEB cbg-meb.nl, and University of Sheffield shef.ac.uk announce two separate workshops on Concepts & Applications of Modelling & Simulation in ADME targeted for scientists from EU Regulatory Agencies. This conforms to the BioSim mission of propagating M&S knowledge using funds from the European Framework 6 Program. Participants from EU Regulatory Agencies will receive free registration to the courses (courtesy of Simcyp & University of Sheffield) and travel assistance (provided by BioSim).

Full details can be found in this pdf on the Simcyp website.
Last Updated ( Friday, 09 May 2008 )
 
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